What might be some diseases resulting in DNA replication failure?


MUTATION:
  • Defects in genes are due to a process called mutation.

  • Mutations are very common, but not always weakening to the carrier.

  • Genetic mutation - medical scientists have identified over ten thousand diseases deriving from genetic mutation.

  • They say to realize that not all mutations are bad, some mutations helped evolution possible in people's opinions.

  • It says given the complexity of DNA replication, mutations happen by chance and you can't control them.



SICKLE-CELL ANEMIA:

  • The only way to get this genetic disease is through a parent, and it is not contagious. ( you can't get it from another person only a parent)

  • It stands in the way with your body's ability to transport oxygen (O2) to other cells in your body.

  • The name "Sickle-cell anemia" comes from the shape of which they're in the body, shaped like half-moon or sickle.

  • This disease leads to lung damage, clogging or damaging blood vessels, and in more serious cases brain and heart damages.

  • Sickle-cell anemia is known as a recessive genetic disease. Thus meaning that in order for a child to get sickle-cell anemia they need to inherit two defective alleles (one of two or more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome) of the relevant gene, must have one from each parent.

  • Elongated red blood cells, pictured here with normal,  doughnut-shaped red blood cells, are characteristic of the genetic  disease sickle-cell anemia.
    Elongated red blood cells, pictured here with normal, doughnut-shaped red blood cells, are characteristic of the genetic disease sickle-cell anemia.



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